Only ANDEMBRY, a monoclonal antibody, inhibits FXIIa at the top of the HAE pathway.
See the ANDEMBRY difference
References: 1. Caccia S, Suffritti C, Cicardi M. Pathophysiology of hereditary angioedema. Pediatr Allergy Immunol Pulmonol. 2014; 27(4):159-163. 2. Kaplan AP, Joseph K. The bradykinin-forming cascade and its role in hereditary angioedema. Ann Allergy Asthma Immunol. 2010;104:193-204. 3. Zuraw BL. Hereditary angioedema. N Engl J Med. 2008; 359(10):1027-1036